Amphisbaena medemi is a species of worm lizard in the family Amphisbaenidae. The species is endemic to Colombia.
The specific name, medemi, is in honor of Federico Medem, who was a Colombian herpetologist, of Baltic German descent.
In Colombia, A. medemi is found in the departments of Atlántico, Cesar, and La Guajira.
The preferred habitat of A. medemi is forest at altitudes of 45–776 m (148–2,546 ft).
A. medemi is oviparous.
