The Great Sandy Desert is an interim Australian bioregion, located in the north west of Western Australia straddling the Pilbara and southern Kimberley regions. It is the second largest desert in Australia after the Great Victoria Desert and encompasses an area of 284,993 square kilometres (110,036 sq mi). The Gibson Desert lies to the south and the Tanami Desert lies to the east of the Great Sandy Desert.
The vegetation of the Great Sandy Desert is dominated by spinifex.
Animals in the region include feral camels, dingoes, goannas (including the large perentie) and numerous species of lizards and birds. Other animal inhabitants include bilbies, mulgara, marsupial moles, rufous hare-wallabies, thorny devils, bearded dragons, and red kangaroos.
Some of the bird-life found within the desert include the rare Alexandra's parrot, the mulga parrot and the scarlet-chested parrot.