Lepidoblepharis grandis is a species of gecko, a lizard in the family Sphaerodactylidae. The species is endemic to Ecuador.
Large for its genus, L. grandis may attain a snout-to-vent length (SVL) of 5.6 cm (2.2 in).
L. grandis is found in Pichincha Province, Ecuador.
The preferred habitat of L. grandis is wet forests at altitudes of 1,190–1,500 m (3,900–4,920 ft).
L. grandis is oviparous.
