Trachylepis is a skink genus in the subfamily Mabuyinae found mainly in Africa. Its members were formerly included in the "wastebin taxon" Mabuya, and for some time in Euprepis. As defined today, Trachylepis contains the clade of Afro-Malagasy mabuyas. The genus also contains a species from the Brazilian island of Fernando de Noronha, T. atlantica, and may occur in mainland South America with Trachylepis tschudii and Trachylepis maculata, both poorly known and enigmatic. The ancestors of T. atlantica are believed to have rafted across the Atlantic from Africa during the last 9 million years.
The generic name Trachylepis literally means "rough-scaled", referring to the fact that most of the species, though superficially smooth-scaled, have three or more slight longitudinal keels on their dorsal scales.