Hemidactylus kyaboboensis grow to a maximum snout–vent length of 80 mm (3.1 in) and a maximum total length of 160 mm (6.3 in). The head is broad. The body has indistinct dark crossbands and more prominent whitish stripes and dots. There is a broad crossband on the neck that reaches the lower tip of the ear hole.
Hemidactylus kyaboboensis have been collected from moist, semi-deciduous rainforests in the Togo Hills of eastern Ghana and Missahöhe in western Togo. These rainforests are habitat islands within the more arid Dahomey Gap.