Hyperolius molleri is a species of frog in the family Hyperoliidae. It is endemic to São Tomé Island. Records from Príncipe now refer to Hyperolius drewesi, described as a distinct species in 2016.
Adult males measure 24–31 mm (0.94–1.22 in) and adult females 31–33 mm (1.2–1.3 in) in snout–vent length. The dorsum is bright green or brown and hasfine spinosities. Juveniles have light dorsolateral lines. The ventrum is uniform white or red. The ventral sides of the legs are white to red. The pupil is horizontal.
