Euprymna scolopes, also known as the Hawaiian bobtail squid, is a species of bobtail squid in the family Sepiolidae native to the central Pacific Ocean, where it occurs in shallow coastal waters off the Hawaiian Islands and Midway Island. The type specimen was collected off the Hawaiian Islands and is deposited at the National Museum of Natural History in Washington, D.C.

Euprymna scolopes grows to 30 mm (1.2 in) in mantle length. Hatchlings weigh 0.005 g (0.00018 oz) and mature in 80 days. Adults weigh up to 2.67 g (0.094 oz).

In the wild, E. scolopes feeds on species of shrimp, including Halocaridina rubra, Palaemon debilis, and Palaemon pacificus. In the laboratory, E. scolopes has been reared on a varied diet of animals, including mysids (Anisomysis sp.), brine shrimp (Artemia salina ), mosquitofish (Gambusia affinis ), prawns (Leander debilis ), and octopuses (Octopus cyanea ).

The Hawaiian monk seal (Monachus schauinslandi ) preys on E. scolopes in northwestern Hawaiian waters.

On June 3, 2021, SpaceX CRS-22 launched E. scolopes, along with tardigrades, to the International Space Station. The squid were launched as hatchlings and will be studied to see if they can incorporate their symbiotic bacteria into their light organ while in space.