Mesalina ercolinii is a species of sand-dwelling lizard in the family Lacertidae. The species is endemic to Somalia.
The specific name, ercolinii, is in honor of Italian ichthyologist Antonio Ercolini.
M. ercolinii is rather large, and is short-legged. The holotype, an adult female, has a snout-to-vent length (SVL) of 6.6 cm (2.6 in).
M. ercolinii is oviparous.