Its main distinguishing feature is dorsolateral stripes that run down the back and end on the posterior.
The species habitat is primarily lowland tropical rainforests as well as inland wetlands of Peru. Little is known about the species' adaptability to modified habitats. The sky-blue poison frog lays its eggs under leaf litter found in its habitat. The larvae are then transported to small streams to hatch.
Due to the decreasing population of sky-blue poison frogs, the species is ranked as endangered by the IUCN. The major threat to the species is habitat loss resulting from human residential and commercial development.