The Colombian black-handed titi (Cheracebus medemi ) is a species of titi, a type of New World monkey, endemic to Colombia. It was originally described in the genus Callicebus in 1963.
Colombian black-handed titis sare relatively small primates with a fluffy coat and a long, bushy tail. This is longer than the body and cannot be used as a prehensile tail. The fur is predominantly black, and in contrast to closely related species, so are the hands. The head is small and roundish, along the throat a white or yellow, collar-like marking extends to the ears.
Colombian black-handed titis are restricted to southern Colombia. Their range is located in the departments of Caquetá and Putumayo. The habitat of this species is tropical rainforests.