Guatemala has 14 ecoregions ranging from mangrove forests to both ocean littorals with 5 different ecosystems. Guatemala has 252 listed wetlands, including five lakes, 61 lagoons, 100 rivers, and four swamps. Tikal National Park was the first mixed UNESCO World Heritage Site. Guatemala is a country of distinct fauna. It has some 1246 known species. Of these, 6.7% are endemic and 8.1% are threatened. Guatemala is home to at least 8,682 species of vascular plants, of which 13.5% are endemic. 5.4% of Guatemala is protected under IUCN categories I-V.
The Maya Biosphere Reserve in the department of Petén has 2,112,940 ha, making it the second-largest forest in Central America after Bosawas. It had a 2019 Forest Landscape Integrity Index mean score of 3.85/10, ranking it 138th globally out of 172 countries.