Afrixalus fornasini is a species of frog in the family Hyperoliidae and is native to Africa. Its common name is Fornasini's spiny reed frog or the greater leaf-folding frog
The specific epithet fornasini is in honour of Italian amateur naturalist Carlo Antonio Fornasini, who collected the type specimen.
It is found in Kenya, Tanzania, Malawi, Mozambique, Zimbabwe, South Africa and possibly Eswatini. Its natural habitats are temperate forest, subtropical or tropical dry forest, dry savanna, moist savanna, temperate shrubland, subtropical or tropical moist shrubland, temperate grassland, subtropical or tropical seasonally wet or flooded lowland grassland, swamps, freshwater marshes, intermittent freshwater marshes, water storage areas, and ponds.