Centrolene ballux is a species of frog in the family Centrolenidae. It is known from a few disjunct localities on the Pacific versant of the Cordillera Occidental in southern Colombia (Nariño Department) and northern Ecuador (Pichincha and Santo Domingo de los Tsáchilas Provinces). Common names golden-flecked glassfrog and Burrowes' giant glass frog have been coined for it.
The specific name ballux is Latin meaning "gold dust", in reference to the tiny gold flecks on the dorsum.
Adult males measure 19–22 mm (0.75–0.87 in) and females 21–23 mm (0.83–0.91 in) in snout–vent length. The snout is rounded. Both fingers and toes are webbed. The tympanum is visible. The dorsum is dark lime green and has minute pale gold-white flecks, which are most numerous on the hind limbs. The tips of digits are yellowish green. The venter is translucent.