Splendrillia skambos is a species of sea snail, a marine gastropod mollusk in the family Drilliidae.
The small, orange to yellowish, claviform shell has a length of 8.8 mm, its diameter 3.6 mm. The smooth protoconch is small (height about 0.8 mm) and consists of 1⅔ whorls, the teleoconch contains 5½ whorls. The axial ribs are strong (with 10-14 ribs on the penultimate whorl). The body whorl has not an inverted cone shape and its dorsum is not prominently humped and is without a distinct varix. The rostrum is not thick. The short siphonal canal is relatively wide and twisted slightly to the right. The aperture is narrowly pear-shaped. The outer lip is not flattened in the middle. The columella is convex and its base is curved to the left.
This marine species occurs off the upper continental slope of Transkei, South Africa.
